More Cialis Information: http://www.cialisvsviagrareviews.com/ Cialis is a trade name for Tadalafil, an erectile dysfunction medication created by Eli Lilly in 2003. Cialis is an effective medication for treating Erectile Dysfunction in males over 40 years old. Real Cialis Review (Testimonial). Only Best Tadalafil ED Medication Reviews (Testimonials) 2015 Chemically, Cialis is called Tadalafil. If you compare Cialis vs Viagra, tadalafil is much better.
Просмотров: 44832 Jim Smith
New research, at a local cancer center, has found that a drug used for erectile dysfunction shows promise for patients with malignant throat tumors.
Просмотров: 177 CBS Miami
More Levitra Information: http://levitranet.com Levitra is the third oral medication for the treatment of Erectile Dysfunction in men. Levitra was created by Bayer AG in 2003. Levitra has very few side effects. Vardenafil can be taken with alcohol and fatty meals. It is a fantastic ED option for men after 40 years old. Real Levitra Review (Testimonial). Best Levitra Reviews (Testimonials) 2015 Online. Levitra is called Vardenafil.
Просмотров: 20915 Jim Smith
“I did write some sad songs in college and maybe that was a good outlet but maybe not good enough.” Check out more awesome videos at BuzzFeedVideo! http://bit.ly/YTbuzzfeedvideo Learn more about mental health week - http://www.buzzfeed.com/bensmith/why-were-doing-mental-health-week#.vnAzxA7bY MUSIC Live Via Satellite Licensed via Warner Chappell Production Music Inc. SFX provided by Audioblocks. (https://www.Audioblocks.com) Footage provided by VideoBlocks http://vblocks.co/x/BuzzFeedYouTube Made by BFMP www.buzzfeed.com/videoteam BASED ON THIS BUZZFEED POST: www.buzzfeed.com/jerrysoda/antidepressed GET MORE BUZZFEED: www.buzzfeed.com/videoteam www.facebook.com/buzzfeedvideo www.instagram.com/buzzfeedvideo www.buzzfeed.com/video www.youtube.com/buzzfeedvideo www.youtube.com/buzzfeedyellow www.youtube.com/buzzfeedblue www.youtube.com/buzzfeedviolet BUZZFEED VIDEO BuzzFeed Motion Picture’s flagship channel. Sometimes funny, sometimes serious, always shareable. New videos posted daily! Subscribe to BuzzFeedVideo today! http://bit.ly/YTbuzzfeedvideo
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This video explains erectile dysfunction and mechanism of action (how it works) of Viagra and its active ingredient sildenafil.
Просмотров: 10752 Let There Be
I was recently prescribed Lisinopril for high blood pressure. I had a terrible side effect with a bad dry cough. The cough was 24/7. It can persist for weeks even if you stop taking Lisinopril. Stay away from this medicine if possible and ask your doctor for an alternative.
Просмотров: 128430 Steve Sherron
Dr. Nissen talks about the safety of Viagra in heart patients ➨ Visit Cleveland Clinic: http://bit.ly/XlxDfr ➨ Visit Health Hub from Cleveland Clinic: http://bit.ly/VBQ3nW ➨ Subscribe to our YouTube Channel: http://bit.ly/W0bJ0y ➨ Like Cleveland Clinic on Facebook: http://on.fb.me/WMFkul ➨ Follow Cleveland Clinic on Twitter: http://bit.ly/Uua1Gs ➨ Follow Cleveland Clinic on Google+: http://bit.ly/136vcTe ➨ Follow Cleveland Clinic on Instagram: http://bit.ly/12gMABx ➨ Connect with Cleveland Clinic on LinkedIn: http://linkd.in/120XfNs ➨ Follow Cleveland Clinic on Pinterest: http://bit.ly/11QqS3A
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The cost of Viagra is between $20 and $30 per pill. If you look at the cost over a period of time and the number of trips to the drug store RejuvaFlow™ is clearly the better option - you only have to visit a doctor every three months for treatment and you get so many other benefits from the procedure. It really is cost effective and non-invasive with no side effects. Patients are carefully screened, people that do not qualify for treatment are those with aortic or brain aneurysms. Overall the procedure is very safe.
Просмотров: 380 Rejuvaheart
A lot of things can kill you - but here are some surprising ones! This Much Will Kill You PART 2: https://youtu.be/IPrndNZ4m6w This Is 200 Calories: https://youtu.be/KMGUmcveQeg SUBSCRIBE (it's free): http://bit.ly/asapsci GET THE ASAPSCIENCE BOOK: http://asapscience.com/book/ Written by Rachel Salt, Gregory Brown and Mitchell Moffit FOLLOW US! Instagram and Twitter: @whalewatchmeplz and @mitchellmoffit Clickable: http://bit.ly/16F1jeC and http://bit.ly/15J7ube AsapINSTAGRAM: https://instagram.com/asapscience/ Facebook: http://facebook.com/AsapSCIENCE Twitter: http://twitter.com/AsapSCIENCE Tumblr: http://asapscience.tumblr.com Vine: Search "AsapSCIENCE" on vine! SNAPCHAT 'whalewatchmeplz' and 'pixelmitch' Created by Mitchell Moffit (twitter @mitchellmoffit) and Gregory Brown (twitter @whalewatchmeplz). Send us stuff! ASAPSCIENCE INC. P.O. Box 93, Toronto P Toronto, ON, M5S2S6 Further Reading: http://www.cdc.gov/niosh/idlh/merc-hg.html Centers for Disease Control and Prevention - Mercury (organo) alkyl compounds (as Hg) https://www.clintox.org/documents/WMDSIG/AACT-WMD-Death_Polonium.pdf Death by Polonium-210 http://coffeefaq.com/site/node/12 Coffee and Caffeine FAQ http://jcb.rupress.org/content/95/2/527.full.pdf Sites of Inhibition of Mitochondrial Electron Transport in Macrophage-injured Neoplastic Cells http://www.rsc.org/chemistryworld/podcast/CIIEcompounds/transcripts/theobromine.asp Royal Society of Chemistry - theobromine. http://jic.sagepub.com/content/28/1/37.short Hypernatremic Disorders in the Intensive Care Unit http://www.aafp.org/afp/2015/0301/p299.html Diagnosis and Management of Sodium Disorders: Hyponatremia and Hypernatremia http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4311234/ Comparative risk assessment of alcohol, tobacco, cannabis and other illicit drugs using the margin of exposure approach http://jeb.biologists.org/content/204/18/3115.full Limits to human performance: elevated risks on high mountains http://www.bbc.com/future/story/20140714-how-long-can-you-go-without-air How long can you go without air? http://www.extremetech.com/extreme/175996-can-a-loud-enough-sound-kill-you Can a loud enough sound kill you? http://www.scientificamerican.com/article/how-long-can-humans-stay/ How long can humans stay awake? http://time.com/3903873/extreme-heat-india-body/ This Is How Extreme Heat Can Kill http://www.researchgate.net/publication/13569135_Influence_of_the_sympathetic_nervous_system_on_renal_function_during_hypothermia Influence of the sympathetic nervous system on renal function during hypothermia
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Erectile dysfunction drug used to treat local man's cancer
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Millions of men are taking PDE5 Inhibitors such as Viagra, Levitra or Cialis. How do PDE5 Inhibitors work? Your body has a system that provides the “gas” necessary to achieve an erection. Your body has another system that applies the break, in order to reduce an erection. Thank goodness for this breaking system, without it we would all be walking around with a permanent erection. However, as we age, the bodies breaking system gets stronger and stronger. That’s one reason it may sometimes be difficult to achieve erection. PDE5 inhibitors work by taking the pressure off of the breaks Releasing the breaks is one thing, pressing the gas can be something quite different. Nitric Oxide is the gas that makes the erection potent, More nitric oxide means longer and stronger erections Stronvivo increases your nitric oxide output and improves erectile function naturally. Stronvivo has been shown to be a great companion to PDE5 inhibitors and has enabled some men to take lower and lower doses of the prescription.
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Why I won't continue with this medication for my bipolar after only taking 2 doses (in addition to Lamictal which HAS proven to work well for me with an antidepressant). I don't say nobody should take it, because not everything works the same for everyone, but this is DEFINITELY not for me. I work three jobs - honestly, do I look fit to work at even ONE job like this?
Просмотров: 8600 Michele
http://www.balancedhealthtoday.com http://www.balancedhealthtoday.com/endosterol.html Medications that treat erectile dysfunction may help alleviate BPH. The ED drugs sildenafil (Viagra), vardenafil (Levitra), and tadalafil (Cialis) have all been shown to reduce BPH symptoms. However, they aren’t currently approved to treat BPH. One 12-week study comparing tadalafil and placebo showed that men who took 5 mg of tadalafil daily had significant improvement in both BPH and ED symptom measures. In an eight-week trial, 108 men who took 10 mg of vardenafil twice daily showed significant improvement in prostate symptoms compared with 113 men who took a placebo. The men were 45 to 64 years old and had a history of BPH. The study also included men who had ED. The results showed improvement in both BPH and ED symptoms in men who had both conditions. http://www.balancedhealthtoday.com/store http://www.balancedhealthtoday.com/store/endosterol.html
Просмотров: 717 Martina Santiago
Sexual impotence—a loss of ability to maintain a full erection—affects most men at some time in their lives. It can be the result of feeling unwelcome, afraid of your own power, or experiencing a sense of inadequacy or depression about yourself. Such feelings strongly influence the behavior of your body. And when you can develop real awareness of how your lover feels, with patience and consideration, psychologically-caused impotence will often clear by itself. Other difficulties in maintaining an erection can be biochemical in nature. In men over the age of 35, this often happens during periods of prolonged stress, after illness, or simply as a result of having lived for too long on convenience foods, so your body has become depleted in essential minerals, trace elements and vitamins. When you have eaten like this, many of your metabolic processes no longer work properly. Then it’s time to make some serious changes in the way you are eating, and keep your alcohol intake to a minimum. In the meantime, there are a number of effective plants for heightening your sexual energy: Mucuna Dopa—this is a powerful Ayurvedic herb, also known as velvet herb. A potent extract from the Mucuna pruriens seed, it heightens brain function, libido and muscle growth. It contains high concentrations of L-Dopa, a neurotransmitter which prompts a positive mental state of action and assertiveness. These are a few of the reasons Mucuna Dopa is an effective sexual enhancer for men. Start by taking one 166mg capsule between meals (containing 100mg of L-Dopa). Never take more than 6 a day and do not use if you are taking MAO inhibitors or any prescription drugs without first getting permission from your medical practitioner. Ginkgo biloba—not only boosts the flow of blood to the brain and enhances memory; it can increase circulation to the penis. The best way to take it for this purpose is in the form of a concentrated 24% standardized extract capsule, once or twice a day. Do not take more, since in large quantities gingko can cause loose bowels and irritability. One research project gave men 80 milligrams of gingko extract three times a day, with excellent results. It not only cleared impotence, it lifted the depression which often accompanies it. You can also get a ginkgo tincture: 1 teaspoon in a little water twice a day. Horny goat weed—has been known for 2000 years in traditional Chinese medicine to enhance both male and female libido. It increases blood circulation to the genitals. A study carried out in 2008 indicated that it can be as effective as Viagra but without the dangerous side-effects. One 1 gram tablet daily between meals is the usual recommended dose. Fava beans—can have an astounding effect on an erection. The first written record of this food’s sexual benefits comes from ancient Rome, where Cicero used it to increase his own passion. Fava is also a good natural source of L-dopa (used to treat Parkinson’s disease). It intensifies erections in many men, which is how fava got its reputation. One way to use fava beans is to make soup from them. Whatever products you buy it is essential that they are top quality and organic. Be warned, there are lots of cheap imitations which do not deliver on their promises. See below for my recommendations. Source Naturals, Mucuna Dopa, 100 mg, 120 Capsules http://www.iherb.com/Source-Naturals-Mucuna-Dopa-100-mg-120-Capsules/14235?rcode=yes026 Paradise Herbs, Ginkgo Biloba, 120 Veggie Caps http://www.iherb.com/Paradise-Herbs-Ginkgo-Biloba-120-Veggie-Caps/4244?rcode=yes026 Planetary Herbals, Horny Goat Weed, Full Spectrum, 1,200 mg, 60 Tablets http://www.iherb.com/Planetary-Herbals-Horny-Goat-Weed-Full-Spectrum-1-200-mg-60-Tablets/1561?rcode=yes026 Bob's Red Mill, Fava Beans http://www.iherb.com/bob-s-red-mill-fava-beans-naturally-blanched-skinless-20-oz-567-g/9904?rcode=yes026 Dragon Herbs, Siberian Ginseng, Super Potency Extract http://www.iherb.com/dragon-herbs-siberian-ginseng-super-potency-extract-2-fl-oz-60-ml/22557?rcode=yes026
Просмотров: 31338 Leslie Kenton
Women in Grand Rapids are asking about the FDA-approved drug to treat women who have a sexual desire disorder, but only a few have gotten prescriptions in the drug’s first month. (Nov. 19, 2015)
Просмотров: 100812 WOOD TV8
http://www.rxwiki.com/stendra Stendra is a prescription medication used to treat erectile dysfunction in men. Stendra belongs to a group of drugs called phosphodiesterase (PDE) inhibitors. These work by increasing blood flow to the penis during sexual stimulation. This increased blood flow can cause an erection. This medication comes in tablet form and is taken typically once a day, on an as needed basis, approximately 30 minutes before sexual activity. Stendra can be taken with or without food. Common side effects of Stendra include headache, flushing, and back pain.
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Some bodybuilders take viagra. Find out why in this video! Please LIKE, COMMENT, and SUBSCRIBE if you haven’t already. Follow Kris Gethin and KAGED MUSCLE on: KM INSTAGRAM: http://instagram.com/KagedMuscleSupps KM TWITTER: http://twitter.com/KagedMuscleLLC KM FACEBOOK: https://www.facebook.com/pages/Kaged-Muscle-Supplements/825389904169567 KM WEBSITE: http://kagedmuscle.com
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http://www.balancedhealthtoday.com http://www.balancedhealthtoday.com/endosterol.html Medications for ED inhibit the enzyme phosphodiesterase-5 (PDE-5). PDE-5 breaks down the chemical cyclic guanosine monophosphate (cGMP). But, cGMP increases blood flow to the penis. So, inhibiting PDE-5 can prevent the breakdown of cGMP. This helps to increase blood flow to the penis. In theory, ED drugs can boost cGMP levels in the bladder and prostate, as well. The increased cGMP and blood flow may allow bladder and prostate cells to relax, leading to greater urinary flow. The studies on ED medication to relieve enlarged prostate symptoms have only looked at short periods of time. And, they only looked at the differences between the ED medications and placebo. The results show promise, but the data is not long-term. The studies have not fully shown that ED drugs are safe and effective to treat urinary symptoms of enlarged prostate. More evidence is needed from studies that directly compare erectile dysfunction drugs with medications for BPH. http://www.balancedhealthtoday.com/store http://www.balancedhealthtoday.com/store/endosterol.html
Просмотров: 44 Martina Santiago
NEOGRA® (sildenafil citrate) Get a free trial with a valid prescription #NEOGRA #Sildenafilcitrate
Просмотров: 610 TAJ PHARMA
Physicians E.D. Center offers safe treatments by licensed professionals for men suffering from erectile dysfunction and/or premature ejaculation. Our seasoned staff of experts provide customized treatments and alternative therapies for men that do not respond to Viagra, Levitra or Cialis. Because we care about your sexual health, we evaluate each patient on an individual basis and use only medications which are proven to be both safe and effective. Let it be known, you don’t have to choose between great sex and your health. Physicians E.D. Centers provide a solution to ED and PE even if you have underlying medical conditions such as high blood pressure, waning sexual desire, weight problems and more. To learn more, contact one of our Physicians E.D. Centers for a discrete and confidential assessment or visit us at http://www.physiciansed.com/
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10% off ISO-BAG discount code: https://isolatorfitness.com/?acc=11 BS3 Underground, Online And In Person Training with Bios3: www.Bios3training.com email@example.com Primeval Labs : primevallabs.com GASP and BETTER BODIES CLOTHING https://elite1fitgear.refersion.com/c/1ea0d for GASP and BETTER BODIES CLOTHING! Bio-Built Workout tv on youtube Alternate Bios3 channel! https://www.youtube.com/channel/UCpBRwUaTaFFkgVfYIKjKo-A ill pump you up https://www.youtube.com/user/IllPumpYouUpcom My Bios3 Facebook https://www.facebook.com/pages/The-Diet-Guy-Bios3Training/292110654144743?ref=hl My Facebook https://www.facebook.com/jerry.ward.923 My Instagram http://instagram.com/jerrywardii# My Twitter https://twitter.com/LucianbagwellN DNA Testing 'The promo code is SetPointJerryWard That will give all viewers a $49 discount on the test at MTLFitness.com
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IntelGenx immediate release oral film Technology, VersaFilm™, is made up of a strip of thin polymeric film comprised of United States Pharmacopeia (USP) components that are safe and approved by the FDA for use in food, pharmaceutical and cosmetic products. Derived from the edible film technology used for breath enhancement strips and initially developed for the instant delivery of savoury flavours to food substrates, the Instant Delivery Film has distinct advantages over existing fast dissolving oral tablets, which make it the application system of choice for indications requiring the immediate onset of action, like migraine, motion sickness, nausea, erectile dysfunction, or seasonal allergies. Learn more about VersaFilm™ here: http://www.intelgenx.com/technologies/tech-wafer.html
Просмотров: 1284 Viral Network Inc
I have had patients who have experienced additional positive side effects from having the RejuvaFlow™ therapy. One man in particular reported that before RejuvaFlow™ treatment for erectile dysfunction, he would get short of breath just walking up the hill to his mailbox. Now he is not short of breath and attributes to the RejuvaFlow™ treatments. The reason is that it RejuvaFlow™ treatment increases blood flow to everything. Your lungs, your brain, heart as well as your pelvic area. So, there are other good side effects that come of this therapy that patients are very happy to have along with a better erection.
Просмотров: 101 Rejuvaheart
Viagra, the "little blue pill" is perhaps the best known of the erectile dysfunction drugs, the other popular ones being Cialis & Levitra. It acts by inhibiting the breakage of a compound called cGMP, which is very closed related to one of the nucleotide bases found in DNA. Molecule built using: www.indigo.com/3D-molecular-model-builder.php
Просмотров: 844 Indigo Instruments
PETACH TIKVA, Israel, Jan. 6, 2015 /PRNewswire/ -- Can-Fite BioPharma Ltd. (NYSE MKT: CANF) (CFBI.TA), a biotechnology company advancing a pipeline of proprietary small molecule drugs that address cancer and inflammatory diseases, today announced its anticipated clinical milestones for calendar 2015. "We are looking forward to a very active year in terms of clinical developments and release of data from key trials including late stage studies for psoriasis," stated Can-Fite CEO Dr. Pnina Fishman. Q1 2015 Data release from Phase II/III psoriasis trial In the first quarter of 2015, Can-Fite plans to announce top line results from its Phase II/III trial of its lead drug candidate CF101 in the treatment of psoriasis. The Company completed enrollment of over 300 patients at 17 clinical centers in the U.S., Europe, and Israel. Previously announced interim results for the first 100 patients were positive. The psoriasis therapeutic market was worth $3.6 billion in 2010 and is forecast to grow to $6.7 billion by 2018, according to estimates of GlobalData. Q1 2015 Completion of commercial A3AR biomarker blood test kit In the first quarter of 2015, Can-Fite anticipates completion of its biomarker blood test kit for the A3 adenosine receptor (A3AR) as a biomarker to predict patient's response to CF101. The kit is designed to test A3AR expression levels prior to treatment with CF101, thereby predicting a patient's response to the drug and providing more personalized medicine. The U.S. Patent and Trademark Office issued Can-Fite a patent for the utilization of A3AR as a biomarker to predict patients' response to CF101 in all autoimmune inflammatory indications. H2 2015 Data release from analysis of Phase II glaucoma trial During the first half of 2015, Can-Fite expects to announce results from its Phase II study of CF101 in the treatment of glaucoma. The 88 patient study is planned to be conducted in two European countries by Can-Fite's subsidiary OphthaliX Inc. (OPLI). The global glaucoma market was estimated by GlobalData to be worth approximately $3 billion in 2010 and CF101 is one of only a few oral drugs developed for glaucoma. The market currently consists primarily of generic eye drop drugs. Oral administration is expected to improve patient compliance. Q4 2015 Completion of patient enrollment for Phase II liver cancer trial By the end of 2015, Can-Fite anticipates completing enrollment of approximately 78 patients in its Phase II trial for its drug candidate CF102 in the treatment of hepatocellular carcinoma (HCC), the most common form of liver cancer. In December 2014, Can-Fite dosed its first patient in the randomized, double-blind, placebo controlled trial to be conducted in the U.S., Europe and Israel. CF102 has been granted Orphan Drug Status by the U.S. Food and Drug Administration and it is also approved for Compassionate Use for Liver Cancer by Israel's Ministry of Health. According to Global Industry Analysts the global market for liver cancer is projected to exceed $2 billion by 2015. Q4 2015 Completion of a working plan for Phase I Sexual Dysfunction trial During 2015 Can-Fite, plans to implement a pre-clinical development program of its next generation drug CF602 for the indication of sexual dysfunction and develop a working plan to file an IND with the U.S. FDA for a Phase I study. In December 2014, Can-Fite received positive pre-clinical data from experimental animal models demonstrating that CF602 improved sexual dysfunction in a dose dependent manner. GlobalData estimates the value of the erectile dysfunction therapeutic market is approximately $2.7 billion with few drugs on the market which includes Viagra, Cialis and Levitra.
Просмотров: 124 CorporateProfile
(2 Aug 2011) SHOTLIST Nonthaburi - 2 August 2011 ++16:9++ 1. Tilt down of officials looking at seized sex pills and toys inside the Food and Drugs Administration (FDA) headquarters 2. Close pull focus of counterfeit viagra pills 3. Close of the word "Viagra" on packaging 4. Mid of seized packets of counterfeit viagra 5. Tilt down of officials looking at goods spread out on table 6. Close of packaging for counterfeit Levitra pills 7. Close of various packs of seized goods 8. Close of pills labelled (English) "Strong Boy" 9. Mid of Dr. Pipat Yingseree, Secretary-General of Thailand''s FDA, showing seized counterfeit pills to the media 10. Close of counterfeit viagra in his hand 11. SOUNDBITE (Thai) Dr. Pipat Yingseree, Food and Drugs Administration (FDA) Secretary-General: "If buyers purchase these products from these stalls and use them without medical advice it could be dangerous to their health and even result in death." 12. Wide pan of officials examining seized goods 13. Various of seized goods on display FILE: Bangkok - November 2003 ++4:3++ ++NIGHT SHOTS++ 14. Wide of Bangkok''s "red light" district 15. Mid of neon sign 16. Mid of girls dancing, legs only visible 17. Mid of neon lights advertising karaoke and Thai massage STORYLINE Thai police presented a haul of counterfeit viagra and other goods to the media on Tuesday, seized from various locations in Bangkok. The pills - often imported from China and India - are sold "under the counter" and help fuel the city''s notorious sex industry. They''re the right size, shape and colour. Even the packaging looks convincing, but the only thing that''s real about these pills is the potential threat to buyers, police say. Thai police raided stalls and shops in the capital last week after complaints from the public. They seized thousands of boxes of counterfeit viagra, levitra and other sexual stimulants, gels and sprays with an estimated street value of around 16-thousand US dollars. According to officials at the Food and Drug Administration, the counterfeit drugs often have far higher doses of the active ingredient than is safe; in the case of some fake viagra, they say, as much as ten times the stated amount. The FDA''s secretary-general, Dr. Pipat Yingseree, said such overdoses could kill. There are no figures on how many people die in Thailand each year as a result of taking sex pills but it''s often cited as a factor in sudden deaths, especially of visiting males. As well as the pills, police also seized sex toys, which are illegal in Thailand under obscenity laws. Bangkok has a well-established sex industry, serving tourists as well as locals. Some of the stalls and shops raided by police last week were in the Nana district, one of the most notorious red light districts. You can license this story through AP Archive: http://www.aparchive.com/metadata/youtube/68e2a12696bfaadc45d52182a23e734e Find out more about AP Archive: http://www.aparchive.com/HowWeWork
Просмотров: 146 AP Archive
In this episode of Ask the Doc, one of our bodybuilders asks about taking Testosterone Replacement Therapy and SARMs simultaneously. He wants to know if there's any need for the SARMs, given everything else he's taking. The next questions asks about if it's useful to take a liver detox while on testosterone. And lastly, is taking Anavar O.K. if you have Crohn's disease. We cover any/all your medical bases!
Просмотров: 329741 MuscleInsider
PETACH TIKVA, Israel, Jan. 27, 2015 /PRNewswire/ -- Can-Fite BioPharma Ltd. (NYSE MKT: CANF) (CFBI.TA), a biotechnology company with a pipeline of proprietary small molecule drugs that address inflammatory and cancer diseases, today reported it has received positive data regarding its CF602 drug candidate in preclinical studies conducted by a third party. CF602 was tested in an experimental animal model of diabetic rats, which similar to diabetic patients, suffer from sexual dysfunction. Erectile dysfunction was assessed by monitoring the ratio between intra-cavernosal pressure (ICP) and mean arterial pressure (MAP) as a physiological index of erectile function. The ICP/MAP for the CF602 treated group improved by 118% over the placebo group. This data is similar to that achieved earlier by sildenafil (Viagra) in preclinical studies. In addition, treatment with CF602 reversed smooth muscle and endothelial damage, in a dose dependent manner, leading to the improvement in erectile dysfunction. CF602 is a novel A3 adenosine receptor allosteric modulator, enhancing the affinity of the natural ligand adenosine to its A3 adenosine receptor. "Our drugs, based on the A3 adenosine receptor platform, have been administered to over 1,200 patients in clinical studies and shown an excellent safety profile. We believe this has the potential to give us a huge advantage over current drugs in the erectile dysfunction market which are known to have adverse effects, hampering diabetic patients and other populations from using them on a daily basis," stated Can-Fite CEO Dr. Pnina Fishman. Based on positive results from this preclinical study, the Company recently announced its plans to initiate a pre-clinical development program for CF602 in order to file an investigational new drug application (IND) with the U.S. Food and Drug Administration to allow human Phase I studies for the indication of sexual dysfunction. Can-Fite has a strong intellectual property position which includes an issued "composition of matter" patent and other pending patent applications protecting the use for sexual dysfunction. GlobalData estimates the value of the erectile dysfunction therapeutic market to be approximately $2.7 billion with few drugs in the market which include Viagra, Cialis and Levitra.
Просмотров: 174 CorporateProfile