Indomethacin prophylaxis in newborn
Просмотров: 396 babysdocnicu
http://usmlefasttrack.com/?p=1344 PDA, close, with, indomethacin, Open, with, Misoprostol, , symptoms, findings, causes, mnemonics, review, what is, video, study, Rapid Review, Clinical presenation, First Aid, for, USMLE, Step 1, images, wiki, define, wikipedia, 2013, videos, exam, prep, easy, What is usmle, mnemonic,
Просмотров: 3648 USMLEFastTrack
Full video: http://www.hcplive.com/hcplive-tv/Clarence-Young-MD-Describes-Iroko-Pharmaceuticals-New-Indomethacin-Reduced-Opioid-Medication-Study-Results Clarence Young, MD, of Iroko Pharmaceuticals, describes the company's new indomethacin, a reduced opioid medication, at the American Pain Society 33rd Annual Scientific Meeting, held April 30, 2014, to May 3, 2014, in Tampa, FL. at the American Pain Society 33rd Annual Scientific Meeting, held April 30, 2014, to May 3, 2014, in Tampa, FL.
Просмотров: 1656 MD Magazine
Video abstract of an original research paper "Effect of a topical copper indomethacin gel on inflammatory parameters in a rat model of osteoarthritis" published in the open access Drug Design, Development and Therapy journal by Yassin NZ, El-Shenawy SM, Abdel-Rahman RF, et al. Objective: We aimed to investigate the effect of topical application of a Copper indomethacin (Cu-Indo) gel preparation on monosodium iodoacetate (MIA) induced arthritis of the knee joint of rats and to test our hypothesis that copper complex of indomethacin could be a more potent anti-inflammatory agent than its parent compound. Methods: After induction of osteoarthritis by the intracapsular injection of 50 μL with 40 mg/mL MIA, we compared the anti-inflammatory efficacy and safety of a topical application of 1% indomethacin gel in a dose of 1 g/kg of the gel (equivalent to 10 mg/kg of the active substance) daily for 3 weeks versus three decremental dose levels of Cu-Indo gel: an equivalent dose, half the dose, and 25% of the dose of indomethacin. Anti-inflammatory efficacy was assessed in all treated groups by measurement of serum inflammatory cytokines: interleukin 6, interleukin 8, and tumor necrosis factor alpha; and by the weekly assessment of knee joint swelling. Joint mobility and motor coordination were also assessed once weekly by the accelerating rotarod apparatus; histopathological examination of affected joints was also performed. Safety of topical application of Cu-Indo (0.25, 0.5, and 1 g/kg) for up to 3 months to rats’ skin was determined by the estimation of a complete blood count, liver and kidney functions, and histopathologic examination for target tissues. Results: Cu-Indo gel at lower doses was superior to or at least as effective as its parent substance, indomethacin, in most of the studied parameters of inflammation. The lowest tested dose of Cu-Indo, corresponding to 25% of the parent substance indomethacin, exhibited the highest efficacy in reducing the elevated serum-tested interleukins and in increasing the time of duration on the rotarod test, whereas its effect on reduction of edema and tumor necrosis factor alpha was comparable to that of the others. After 3 months of daily application, there were no notable changes in studied safety parameters with the lowest Cu-Indo dose, but the group treated with the higher dose showed a small but statistically significant increase in serum-unconjugated bilirubin and a slight decrease in hemoglobin levels, red blood cells, and platelet count, with normal indices denoting a slight hemolytic effect at the highest dose. Conclusion: Cu-Indo gel has potent anti-inflammatory activity against joint inflammation in the MIA-treated rat model of osteoarthritis at doses of 0.25, 0.5, and 1 g/kg. The lowest studied dose was better on both safety and efficacy parameters Read the original article here: http://www.dovepress.com/effect-of-a-topical-copper-indomethacin-gel-on-inflammatory-parameters-peer-reviewed-article-DDDT
Просмотров: 964 Dove Medical Press
This video will teach you how to remove a suppository from the most common molds that we use at the pharmacy and explain how storage and insertion techniques. For more question please call the Medicine Shoppe Pharmacy in New Philadelphia, Ohio at 830-1028. The Medicine Shoppe is an accredited compounding pharmacy by PCAB.
Просмотров: 117469 gomedshoprx
Whiteboard JPG at http://www.memorizingpharmacology.com Pharmacology review of musculoskeletal pharmacology. Starting to work out the kinks in Chapter 2 Musculoskeletal of Drawing Pharmacology
Просмотров: 1039 Tony PharmD
http://stop-ear-ringing.info-pro.co My Ears Are Ringing, Ringing In My Ear, Hearing Aids For Tinnitus, Treatment Of Tinnitus. What Causes Tinnitus? First the good news - we know what causes tinnitus. And now the bad news - conventional medical science cannot cure it. Not permanently at least. Sure enough, your doctor would suggest a few remedies, and it may seem to you that the noises you hear are going down. As a result, you begin to relax believing that a pesky problem has been resolved. But suddenly the sounds return again. This is a very common problem actually. So let us turn to the causes instead, and see whether we can try to solve the issue from this end. Here Are Some of the Most Common Causes of Tinnitus Exposure to noise - Did your mom always tell you in your younger days to turn down the volume? She was right. Exposure to loud noise can give you tinnitus. In fact, rock musicians, and those who work with them, or in night clubs often have it. Those who work in construction sites also have tinnitus. So turn down that volume while you still can. You could begin to hear all kinds of noises if you have been exposed to just a single high-pitched noise. Or it could be due to a continuous attack of loud noises close to your ear. This is what happens. Prolonged exposure to noise can damage the Cochlea and cause tinnitus. So if you cannot simply stay away from all that noise, at least get some protection. Use an ear plug when you can. Head injury - Take care of your head because a severe blow or a slight bang could make you hear the tinnitus noises. The head is of course one of the most sensitive parts of the human body. But some people cannot live without an injury, such as those who are into sports - boxers and football players. That's why athletes are more prone to a tinnitus attack. Even a dental surgery could make you hear them. Ear infections and other ear problems - An ear infection, and even sinus can lead to tinnitus as well. When there is an allergy or a sinus infection, the mucous thickens within the inner ear, and this causes more pressure. The extra pressure can lead to tinnitus. Meniere's disease, where the fluid level goes up inside the middle ear is another reason. It could even cause hearing loss. Prescription medications - Conventional drugs often cause side effects, and tinnitus is one of them. Actually, all kinds of drugs have been blamed for instigating this condition. Such as antibiotics like Aminoglycosides, Erythromycin and Vancomycin, Aspirin or medicines containing it. Anti inflammatory drugs like Advil, Aleve, Anaprox, Clinoril, Feldene, Indocin, Lodine and Motrin have also been blamed. Sometimes people heard noises after taking chemotherapy agents such as Cisplatin, Nitrogen Mustard and Vincristine. And some others have even blamed quinine and loop diuretics for this. Stress - You must already know that excessive stress is not good for your health. It could result in all kinds of medical problems, and some of them can also be fatal. Stress can cause tinnitus too. A lot of it is damaging for your immunity, and this can lead to a misfire in the sound/brain waves. This adversely affects your nervous system, and makes you hear the noises. Depression - Some people believe that depression causes tinnitus. And there are those who say that tinnitus causes depression. But most of them agree that there is a relation between these two. And anyway, if your tinnitus is bothering you endlessly, it can make you depressed. Naturally this will further complicate matters. Take on these causes to achieve a permanent relief from tinnitus. Just tackling the symptoms will never work. After all, if the causes remain, the symptoms are bound to return. The only way you could ever get rid of your tinnitus for good is by following the holistic approach to healing. By using a multidimensional treatment for tinnitus, we are tackling all tinnitus causative factors and eliminating these triggering elements from the root. This is the only path for permanent freedom from tinnitus. The Only Holistic System In Existence That Will Teach YOU How To Quickly and Permanently Cure Your Tinnitus, INSTANTLY Relieve The Ringing In Your Ears, Rebalance Your Body and Achieve Tinnitus Freedom! Click here: http://stop-ear-ringing.info-pro.co Subscribe to our channel https://www.youtube.com/watch?v=A4xVu74pjSw My Ears Are Ringing, Ringing In My Ear, Hearing Aids For Tinnitus, Treatment Of Tinnitus
Просмотров: 40 Barrett's Esophagus Diet