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Pharmacology - Glucocorticoids
 
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http://armandoh.org/ https://www.facebook.com/ArmandoHasudungan Support me: http://www.patreon.com/armando Instagram: http://instagram.com/armandohasudungan Twitter: https://twitter.com/Armando71021105 Aracidonic Acid: http://www.youtube.com/watch?v=VSc9U8JaWYg Osteoporosis: http://www.youtube.com/watch?v=2cz2rkBy2rg
Просмотров: 217769 Armando Hasudungan
Corticosteroid Mnemonics in Pharmacology for Medical  and Dental Professional Exams ,Session 1
 
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This video deals with Quick n easy way to memorise about Corticosteroid drugs.Corticosteroids are a class of steroid hormones that are produced in the adrenal cortex of vertebrates, as well as the synthetic analogues of these hormones. Two main classes of corticosteroids, glucocorticoidsand mineralocorticoids, are involved in a wide range of physiologic processes, including stress response, immune response, and regulation of inflammation, carbohydratemetabolism, protein catabolism, blood electrolyte levels, and behavior.[1]Synthetic pharmaceutical drugs with corticosteroid-like effects are used in a variety of conditions, ranging from brain tumors to skin diseases. Dexamethasone and its derivatives are almost pure glucocorticoids, while prednisone and its derivatives have some mineralocorticoid action in addition to the glucocorticoid effect. Fludrocortisone(Florinef) is a synthetic mineralocorticoid. Hydrocortisone (cortisol) is typically used for replacement therapy, e.g. for adrenal insufficiency and congenital adrenal hyperplasia. Medical conditions treated with systemic corticosteroids:[3][4] Allergy and respirology medicineAsthma (severe exacerbations)Chronic obstructive pulmonary disease(COPD)Allergic rhinitisAtopic dermatitisHivesAngioedemaAnaphylaxisFood allergiesDrug allergiesNasal polypsHypersensitivity pneumonitisSarcoidosisEosinophilic pneumoniaInterstitial lung diseaseDermatologyPemphigus vulgarisContact dermatitisEndocrinology (usually at physiologic doses)Adrenal insufficiencyCongenital adrenal hyperplasiaGastroenterologyUlcerative colitisCrohn’s diseaseAutoimmune hepatitisHematologyLymphomaLeukemiaHemolytic anemiaIdiopathic thrombocytopenic purpuraMultiple MyelomaRheumatology/ImmunologyRheumatoid arthritisSystemic lupus erythematosusPolymyalgia rheumaticaPolymyositisDermatomyositisPolyarteritisVasculitisOphthalmologyUveitisKeratoconjunctivitisOther conditionsMultiple sclerosisOrgan transplantationNephrotic syndromeChronic hepatitis (flare ups)Cerebral edemaIgG4-related diseaseProstate cancerTendinosisLichen planus Topical formulations are also available for the skin, eyes (uveitis), lungs (asthma), nose (rhinitis), and bowels. Corticosteroids are also used supportively to prevent nausea, often in combination with 5-HT3 antagonists (e.g.ondansetron). Typical undesired effects of glucocorticoids present quite uniformly as drug-induced Cushing's syndrome. Typical mineralocorticoid side-effects are hypertension (abnormally high blood pressure), hypokalemia (low potassium levels in the blood), hypernatremia (high sodium levels in the blood) without causing peripheral edema, metabolic alkalosis and connective tissue weakness.[5] Wound healing or ulcer formation may be ibhibited by the immunosuppressive effects. Clinical and experimental evidence indicates that corticosteroids can cause permanent eye damage by inducing central serous retinopathy (CSR, also known as central serous chorioretinopathy, CSC).[6] A variety of steroid medications, from anti-allergy nasal sprays (Nasonex, Flonase) to topical skin creams, to eye drops (Tobradex), to prednisone have been implicated in the development of CSR.[7][8] Corticosteroids have been widely used in treating people with traumatic brain injury.[9] A systematic review identified 20 randomised controlled trials and included 12,303 participants, then compared patients who received corticosteroids with patients who received no treatment. The authors recommended people with traumatic head injury should not be routinely treated with corticosteroids.[10] Use of corticosteroids has numerous side-effects, some of which may be severe: Neuropsychiatric: steroid psychosis,[13] and anxiety,[14] depression. Therapeutic doses may cause a feeling of artificial well-being ("steroid euphoria").[15] The neuropsychiatric effects are partly mediated by sensitization of the body to the actions of adrenaline. Therapeutically, the bulk of corticosteroid dose is given in the morning to mimic the body's diurnal rhythm; if given at night, the feeling of being energized will interfere with sleep. An extensive review is provided by Flores and Gumina.[16]Cardiovascular: Corticosteroids can cause sodium retention through a direct action on the kidney, in a manner analogous to the mineralocorticoid aldosterone. This can result in fluid retention and hypertension.Metabolic: Corticosteroids cause a movement of body fat to the face and torso, resulting respectively in "moon face" and "buffalo hump". and away from the limbs. Due to the diversion of amino-acids to glucose, they are considered anti-anabolic, and long term therapy can cause muscle wasting[17]Endocrine: By increasing the production of glucose from amino-acid breakdown and opposing the action of insulin, corticosteroids can cause hyperglycemia,[18] insulin resistance and diabetes mellitus.[19]Skeletal: Steroid-induced osteoporosis may be a side-effect of long-term corticosteroid use. Use of inhaled corticosteroids amon
Просмотров: 1041 Dr Anshuman Tripathi
Renal tubular acidosis - causes, symptoms, diagnosis, treatment, pathology
 
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What is renal tubular acidosis (RTA)? RTA is a type of metabolic acidosis caused by the kidneys failure to properly acidify the urine. Find more videos at http://osms.it/more. Study better with Osmosis Prime. Retain more of what you’re learning, gain a deeper understanding of key concepts, and feel more prepared for your courses and exams. Sign up for a free trial at http://osms.it/more. Subscribe to our Youtube channel at http://osms.it/subscribe. Get early access to our upcoming video releases, practice questions, giveaways and more when you follow us on social: Facebook: http://osms.it/facebook Twitter: http://osms.it/twitter Instagram: http://osms.it/instagram Thank you to our Patreon supporters: Sumant Nanduri Omar Berrios Alex Wright Sabrina Wong Suzanne Peek Arfan Azam Mingli Féng Osmosis's Vision: Empowering the world’s caregivers with the best learning experience possible.
Просмотров: 93329 Osmosis
Pharmacology Tips Loop Diuretics  Lasix
 
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EmpoweRN.com Thank you so much for watching my channel! For the additional resources you can visit here: http://empowern.com/2015/03/pharmacology-loop-diuretics-lasix/ Also, to enter the giveaway all you have to do is: 1. Post a comment 2. Subscribe to the channel. Winner will be announced via email here: http://goo.gl/NO7T7b I would like to thank the video contributors: Rizalyn Joy Gadugdug Maria Salvacion Gonzales Yasmin Hashmi Artem Shestakov And Babar Hayatrana Disclaimer: These videos are intended for entertainment purposes only. Please follow the policy and procedures that your institution requires. Please note that the views, ideas & opinions expressed on this channel and in the videos on this channel are not necessarily of those of my employer or institution. The views expressed on this channel and in the videos channel do not represent medical advice. If you have specific medical concerns, please contact your physician. In order to protect patient privacy, all patient identifiers in all videos have been deleted or altered. The views expressed on this channel and in the videos on this channel are personal opinions. I am not an expert nor do I dispense medical advice or procedural specifications. The information I present is for general knowledge and entertainment purposes only. You need to refer to your own medical director, teachers and protocols for specific treatment information. It is your responsibility to know how best to treat your patient in your jurisdiction. Furosemide (Lasix) - Loop Diuretics Generic Name: Furosemide Brand Name: Lasix Furosemide also known as Lasix is a loop diuretic commonly use to treat fluid retention and edema. Which can be associated with Congestive Heart Failure (CHF), cirrhosis of the liver, and many kidney disorders. It is also sometimes use to treat hypertension alone or in combination with other anti-hypertensive drugs. Diuretics are medications that increases the amount of water that passes through the kidneys as urine, thus, it is often called water pill. Lasix belongs to the group known as Loop diuretics. There a few types of diuretics and loop diuretics are just one type. It works by interfering with the sodium, potassium and chloride symporter. A symporter is a protein membrane that manages the transport of molecules across a cell membrane. The symporter that lasix interacts with is found in the thick ascending limb of the loop of Henle. What it does is………. inhibits the reabsorption of salt (Na+) and Chloride (Cl-). Since the Salt and Chloride will be leaving the body system through the loop of henle this means that water will also follow…. causing more water pass through the kidney. Which will ultimately mean, less fluid remaining in the blood stream. Once Lasix is received the system will then compensate the loss by absorbing any fluid accumulated in the tissues, such as in the lungs or legs, back to the blood stream. This will cause more fluid to be in the blood stream. Which once again pass through the kidney, which will also be excreted in the urine, since the loop diuretic inhibits its reabsorption. This mechanism, is what makes loop diuretics a treatment for fluid retention also known as edema. It can therefore, ease symptoms of edema such as breathlessness caused by congestion of fluid in the lungs which patients diagnosed with CHF, cirrhosis of the liver, nephrotic syndrome and other edematous states may encounter. Lasix is available in forms that can be taken orally and intravenously. When taken intravenously, it is considered to be twice as strong. Parenteral or intravenous Furosemide is indicated when a fast acting and an intense diuresis is needed such as in acute pulmonary edema and cerebral edema. It also indicated when oral therapy is not possible because of problem with absorption in the intestine or for other reasons. Parenteral administration should be observed only in hospital or outpatient clinics. However, in cases of emergency that furosemide should be given right away outside hospital setting, recommended doses should be closely adhered to and patient must be closely monitored. Contraindication: Furosemide should not be taken if your patient cannot urinate. Severe Hypokalemia - is a major contraindication. This means low potassium. Lasix can cause a dramatic decrease in potassium level which could cause lethal cardiac arrhythmias Other contraindications include: Hypotension or low blood pressure Lasix should be used with extreme caution for patients who have a diagnosis of Systemic Lupus Erythematosus because it may May
Просмотров: 80590 EmpoweRN
Aldosterone raises blood pressure and lowers potassium | NCLEX-RN | Khan Academy
 
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See how Aldosterone effects the principal cells of the kidney to raise BP and lower potassium. Rishi is a pediatric infectious disease physician and works at Khan Academy. Created by Rishi Desai. Watch the next lesson: https://www.khanacademy.org/test-prep/nclex-rn/rn-renal-system/rn-renal-regulation-of-blood/v/aldosterone-removes-acid-from-the-blood?utm_source=YT&utm_medium=Desc&utm_campaign=Nclex-rn Missed the previous lesson? https://www.khanacademy.org/test-prep/nclex-rn/rn-renal-system/rn-renal-regulation-of-blood/v/angiotensin-2-raises-blood-pressure?utm_source=YT&utm_medium=Desc&utm_campaign=Nclex-rn NCLEX-RN on Khan Academy: A collection of questions from content covered on the NCLEX-RN. These questions are available under a Creative Commons Attribution-NonCommercial-ShareAlike 3.0 United States License (available at http://creativecommons.org/licenses/by-nc-sa/3.0/us/). About Khan Academy: Khan Academy offers practice exercises, instructional videos, and a personalized learning dashboard that empower learners to study at their own pace in and outside of the classroom. We tackle math, science, computer programming, history, art history, economics, and more. Our math missions guide learners from kindergarten to calculus using state-of-the-art, adaptive technology that identifies strengths and learning gaps. We've also partnered with institutions like NASA, The Museum of Modern Art, The California Academy of Sciences, and MIT to offer specialized content. For free. For everyone. Forever. #YouCanLearnAnything Subscribe to Khan Academy’s NCLEX-RN channel: https://www.youtube.com/channel/UCDx5cTeADCvKWgF9x_Qjz3g?sub_confirmation=1 Subscribe to Khan Academy: https://www.youtube.com/subscription_center?add_user=khanacademy
Просмотров: 250598 khanacademymedicine
Corticosteroids - Chemical Structure
 
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How it works: http://fopcupedia.org/blog/how-it-works/ Mind Map: https://goo.gl/exhxG5 0:02 Prednisone 0:05 Cortisone 0:08 Hydrocortisone 0:11 Prednisolone 0:14 Methyl Prednisolone 0:17 Beclomethasone 0:21 Betamethasone 0:24 Dexamethasone 0:27 Fludrocortisone 0:30 Triamcinolone 0:33 Triamacetonide 0:36 Fluocinolone Acetonide 0:40 Ciclesonide 0:46 Aldosterone 0:49 11-Deoxycortisone Acetate 0:53 Spironolactone 0:57 Thilostane 1:03 Mind Map
Просмотров: 73 fopcupedia
Dr.Ahmed Abd El-Rahman - Hormones 4 - TopicCorticosteroids - Part 3
 
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Subject : Pharmacology Tuesday - 18th, March 2014 Contents :- * Corticosteroids - Aldosterone - Des-Oxy-Corticosterone - Fludrocortisone Acetate *ACTH -Hydrocortisone *Theraputic uses of Glucocorticoids
Просмотров: 2670 Kasr Al-Ainy - 3rd Year (2011-2017) Channel
Dr.Ahmed Abd El-Rahman - Hormones 4 - TopicCorticosteroids - Part 2
 
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Subject : Pharmacology Tuesday - 18th, March 2014 Contents :- * Corticosteroids - Aldosterone - Des-Oxy-Corticosterone - Fludrocortisone Acetate *ACTH -Hydrocortisone *Theraputic uses of Glucocorticoids
Просмотров: 3387 Kasr Al-Ainy - 3rd Year (2011-2017) Channel
Fluorine
 
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Fluorine is a chemical element with the symbol F and atomic number 9. It is the lightest halogen and exists as a highly toxic pale yellow diatomic gas at standard conditions. As the most electronegative element, it is extremely reactive: almost all other elements, including some noble gases, form compounds with fluorine. Among the elements, fluorine ranks 24th in universal abundance and 13th in terrestrial abundance. Fluorite, the primary mineral source of fluorine, was first described in 1529; as it was added to metal ores to lower their melting points for smelting, the Latin verb fluo meaning "flow" became associated with it. Proposed as an element in 1810, fluorine proved difficult and dangerous to separate from its compounds, and several early experimenters died or sustained injuries from their attempts. Only in 1886 did French chemist Henri Moissan isolate elemental fluorine using low-temperature electrolysis, a process still employed for modern production. Industrial synthesis of fluorine gas for uranium enrichment, its largest application, began during the Manhattan Project in World War II. This video is targeted to blind users. Attribution: Article text available under CC-BY-SA Creative Commons image source in video
Просмотров: 1063 Audiopedia
Hormonal Imbalance | On Call with the Prairie Doc | April 12, 2018
 
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Dr. Rick Holm, The Prairie Doc, is joined by Mark Oppenheimer, M.D., to discuss Hormonal Imbalance. They touch on the normal hormone functions of thyroid, pancreas, adrenal gland, pituitary, when there is too much or too little hormone. The will also talk about what treatments are available to slow down hormone excess, or replace hormone depletion. Mark J. Oppenheimer, M.D. has been practicing endocrinology in Sioux Falls since 1989. He opened Oppenheimer Endocrinology in 2005. Since then, the practice has grown to serve patients across the Midwest. Dr. Oppenheimer is also a clinical associate professor at the Sanford School of Medicine of the University of South Dakota. Learn more: https://www.PrairieDoc.org Like us on Facebook: https://www.facebook.com/ThePrairieDoc Follow us on Twitter: https://www.twitter.com/ThePrairieDoc Follow us on Instagram: https://www.instagram.com/ThePrairieDoc
Просмотров: 44 The Prairie Doc
Addison's disease
 
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Addison's disease is a rare, chronic endocrine disorder in which the adrenal glands do not produce sufficient steroid hormones . It is characterised by a number of relatively nonspecific symptoms, such as abdominal pain and weakness, but under certain circumstances, these may progress to Addisonian crisis, a severe illness which may include very low blood pressure and coma. This video targeted to blind users. Attribution: Article text available under CC-BY-SA Creative Commons image source in video
Просмотров: 2392 encyclopediacc