Please subscribe! https://goo.gl/XV4H04 New Videos Every Other Week! The story of how Tylenol convinced the world it was more than just acetaminophen and better than aspirin. For more information on the subject of Acetaminophen and the history of Tylenol I recommended:
Nancy West Communications: http://goo.gl/AY9xDx
& Pro Publica's Report: https://goo.gl/KWKccL
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The history of acetaminophen dates back to the latter part of the 19th century. The
substance was first described in chemical literature in 1878. In 1886, Drs. Arnold Cahn
and Paul Hepp of France were treating a patient suffering from intestinal parasites. They
had been investigating naphthalene for its beneficial effect in the treatment of this
problem. When their drug supply ran out, they ordered more from a local pharmacy. An
inexperienced pharmacist mistakenly filled the prescription with acetanilide.
The physicians found that acetanilide produced marked fever reduction in one of their
patients who, along with intestinal parasites, had a febrile disease. As Drs. Cahn and
Hepp continued to prescribe acetanilide, they also noticed its analgesic properties.
It wasn't until 1899, however, that the relationship between acetaminophen and
acetanilide was discovered by Karl Morner of Germany. He learned that acetanilide is
metabolized in the body to become acetaminophen.
Ten years later, another German physician, Joseph Freiher von Mering, first synthesized
acetaminophen. Although his research confirmed that the drug was effective against pain
and fever, von Mering recommended extensive investigation into all analgesics and
Acetaminophen was not prescribed nor studied any further until 1949 when research on
chemically related drugs revived interest in the compound. Modern research techniques
and clinical use in England confirmed the effectiveness and safety of acetaminophen as a
fever and pain reliever.
In the late 1940s, McNeil Laboratories, as the company was then known, had defined as a
new product objective an analgesic which would be different, available for marketing and
prescription only. At about the same time, James Roth, M.D., a University of
Pennsylvania Graduate School of Medicine gastroenterologist, was lecturing throughout
the United States about the dangers of aspirin. Subsequently, he began advocating for
APAP. Dr. Roth became a pr
In the spring of 1955, McNeil introduced TYLENOL Elixir for Children, the company's
first single ingredient acetaminophen product. The outstanding success of TYLENOL
was attributed to a unique marketing strategy:
+CalabusDabus Yes correct! McNeil Labs had such success with Tylenol/Acetaminophen they decide to do the same thing with ibuprofen; This time marketing it as 'Motrin'. (That's the Johnson &a Johnson--ergo McNeil labs, brand of ibuprofen.)
in my country pharmaceutics must have, along side the more commercial products, what it is called "generics". it's the "white brand" version of a drug that basically has the same active substance. making doctors prescribe generics is also something that is politically considered.
Yes! The problem has gone down in recent years... but a sizable amount of doctors in the U.S. used to receive 'kick backs' from pharmaceutical companies for prescribing their brand of medication. Also thanks for watching!
+linkcell That's interesting your country is thinking about legislating the requirement to prescribe generics. In the United states any one pharmaceutical lobby arm is too strong to make something like that even feasible.
hey man, this video is great. I really like your visual approach and the old photos and videos. the sound is getting better too. I like the girl's voice (lacy?) and I think a more conversation like format would be enjoyable - especially since your voices are so complementary different in tone and articulation. I would suggest you would try doing a clip more based on this format just try it.
but whatever you do, don't stop doing your videos in the format you are used to - they are getting better and better!
You didn't even mention the huge number of overdoses due to acetaminophen that result in the deaths of many, many healthy people? Or the connection with prescription painkillers and how it is a contributing factor in the deaths of opiate addicts? How Tylenol has been on the losing end of multiple court cases and how the FDA would recommend regulation so that it would not be an over the counter medication? How about the poisoning case where there quality assurance was so lax that someone randomly dosed a bunch of people with poison or the fact that Tylenol tried to cover it up and that when it happened again by accident they discovered that there was a bad batch and told no one? Generics are the least of ones worries in this case.
+theWild-man1307 Thanks for watching! While I agree with you, this movie wasn't about the dangers of acetaminophen--Pro Publica already has an excellent piece on the health problems of acetaminophen; I link to it in the video description. Additionally I have a different video where I talk about the problems of combing acetaminophen with opioid painkillers, you can watch it here: https://goo.gl/vDPf1e
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