Could anyone comment further on potential liver damage? I'm guessing it's only thought to possibly cause it due to increased liver enzymes, but I would really like more information on how potentially dangerous it may be. I've been interested in trying adrafinil for a while now. Would be nice if I could just, y'know, try modafinil, though.
How about the fact that you can legally take adrafinil without a prescription but if you don't have a prescription for modafinil and you get caught with modafinil it is a felony charge of drug possession? Is that not a benefit of adrafinil over modafinil? A legal benefit.
First I have not used either drug. I am just doing some research before I try Adrafinil. Now if Adrafinil cause elevated liver enzymes then Modafinil must do the same. If not then the elevated liver enzymes must be secondary to the increased amount of Modafinil acid that is produced since this is the only difference I see. Both drugs metabolize to Modafinil acid per your discussion. The difference is if you take Adrafinil there 2 points where the pathway goes to Modafinil acid and 1 with Modafinil. So I don't see why one drug would increase liver function test not the other unless it is caused by the Modafinil acid. If that is the case then still both should cause elevated liver test. You would just need higher dose of Modafinil to get the same side effects. Maybe some else is missing with the Adrafinil pathway. I hope that makes sense. Use both sparingly.
The problem with Modafinil is that its is a Schedule IV controlled substance, and therefore cannot be purchased without a prescription. I've found Adrafinil to be one of the few neurotropics that is indeed effective to a clearly discernable degree -- worth buying. I'd purchase Modafinil only if it were legal to do so. Regarding liver enzymes, I have a healthy liver, but take N-Acetyl-L-Cysteine (a liver protector, as it is converted to glutathione), and wonder if it offers protection from whatever metabolite of Adrafinil might be responsible for elevated liver enzymes. In addition to Adrafinil, I've found amazing results from caffeine and aspirin in combination (please google research on this) and, just recently, caffeine and L-Theanine (again, google for research).
Okay, I see your point and I do agree with you completely; Adrafinil is a less effective version of Modafinil. Although while it may be a prodrug and most of it is wasted being converted into Modafinil in the liver, it is legal and is an over the counter substance while as Modafinil, you need a prescription. So that being said, for someone unable to obtain Modafinil, do you think that Adrafinil would be somewhat of a viable substitute? I'd appreicate and would very much respect a response if you could, thanks. great vid btw, you really know what your talking about unlike most other videos i've come across.
Patrick O'Neill your brain gets the same chemical with either modafinil or adrafinil, it's not less effective. It's just less potent, meaning you need more of adrafinil to achieve the same effects as modafinil
May I also add how relieving it is to finally see a video from someone who isn't promoting these drugs as the "magic limitless pill" or trying to get me to buy something but instead is stating the facts. Not swaying to one side or the other, Truly Impartial. I commend and thank you sir.
Great video. Very eloquently put. I ordered adrafinil not knowing it was different from modafinil. Took 600mgs with no effect. Could not figure out what was happening so I searched through several stupid videos and reviews before I found this one that put my mind to ease. Yes, I think taking adrafinil is stupid and a waste of money and liver. Time to order modafinil (The Real Deal).
I would love to see a adderall vs modafinil! I know they are quite different, but they are used for the same purpose (study wise, I know they have other and separate uses as well). Anyway keep up the great work!
Modafinil might be weaker than Adderall, but there's more downsides & side effects with the latter drug....
It seems like Modafinil gives you smoother & cleaner energy, while some people get more of a rush from Adderall. Both could give a person sleep problems, but continued Adderall use could result in nervousness, vomiting, weight loss, decreased sex drive, and heart palpations, to name a few....
Also, there's the fact that Modafinil is more legal than Adderall. Some countries require a prescription in order for Modafinil to be used legally.
Adderall, on the other hand, is banned from most sports and you can even get arrested for using it.
People are free to use either one, but I'm just giving out my take on it.
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